MEDICAL TOPICS- NEPHRITIS

Nephritis


Summary

Description

  • Denotes the clinical syndrome of active glomerulonephritis, characterized by blood in urine (usually microscopic) with  red blood cells in the urine sediment and minimal-to-moderate proteinuria
  • May be associated with infectious, postinfectious, malignant, or autoimmune disease, or idiopathic
  • In severe cases, may be associated with decreased kidney function , salt and water retention, and hypertension ( high blood pressure)
  • Results from inflammation in the glomeruli, which may be focal or diffuse
  • Therapy is generally supportive while treating the associated disease, but specific therapies are available for a limited subset of patients. Renal biopsy will be needed in most cases
  • Prognosis depends on etiology and degree of renal damage

Synonyms

  • Glomerulonephritis
  • Acute nephritis
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